CD2 Antikörper

Produktnummer ABIN3024312

Der Maus Monoklonal Anti-CD2 Antikörper wurde für FACS, IF, WB und Func validiert. Er ist geeignet, CD2 in Proben von Human und Cat zu detektieren.

Kurzübersicht für CD2 Antikörper (ABIN3024312)

Target: CD2

Reaktivität: Human, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Klon: HuLy-m1

Produktdetails anti-CD2 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Human thymocytes were used as the immunogen for the CD2 antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD2 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL, Western blot: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.